>A team of little girls.
>Each are disabled in some way.
>Each possess an extraordinary power that somehow compliments their disability.
>The blind girl is invisible, which helps because invisibility would blind you anyway.
>The deaf-mute girl is a telepath, which helps because she does not confuse the thoughts she hears for voices.
>The legless girl can fly, perhaps she also has some limited form of telekinetic abilities (like the girl in elfen lied), perhaps she is also armless.
>A girl with scars might also have control over the elements - fire, ice, both, whatever.
>more exotic bizarre traits might exist that grant powers yet also place the girl outside of normal humanity, a girl that looks like the fresh bloodless corpse of a hairless albino, she possesses powers associated with the undead, but also the weaknesses, a girl who is the mythical "aquatic ape" form of humanity, like any marine mammal she can't live on land for too long but is insane in the water, a girl who is unusually tall and strong for her age, se manages to still be cute even though she's a hypertrophic giantess who is also fated to become very well-endowed in all ways with a killer hourglass figure when she grows up (though she will be head and shoulders above all the men even when barefoot), a girl who can temporarily take the form of anyone or anything she consumes a DNA sample from, the amount of it she takes in determines how long she can hold the form, she can also partially shift into her acquired form by taking on only specific traits from her sample, and this consumes less of it, also she can mix and match traits from various genetic samples to become a combination of them, her weakness being that her true form is little more than a puddle of goo, she's a goo-girl. IDK, maybe someone more creative than me could work out something better?